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2 common methods of RNA extraction:
https://en.wikipedia.org/wiki/Acid_guanidinium_thiocyanate-p...
https://sci-hub.se/10.1038/nprot.2006.83
the other methodology is quick to perform, but requires silica columns.
https://en.wikipedia.org/wiki/Spin_column-based_nucleic_acid...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC269651/
The problem is outlined here:
https://www.fda.gov/medical-devices/emergency-situations-med...