Hacker News

Top stories

Live mirror
30 storiesupdated just nowView source snapshot
  1. Nvidia announces native GPU programming in Rust(nvidia.com ↗)
    150comments
  2. Keys Not Included: recovering the signing keys for US driver's license barcodes(ryan.science ↗)
    discuss
  3. Training a 4B model to produce 81% faster query plans than Postgres(rohanbansal.com ↗)
    92comments
  4. Xiaomi Mimo 2.6 live post-training dashboard(xiaomi.com ↗)
    81comments
  5. DeepSeek-v4.1 Flash: Pushing the Limits of KV Cache Compression(zartbot.github.io ↗)
    3comments
  6. Breaking the 1.58-bit Barrier for Ternary LLMs(arxiv.org ↗)
    21comments
  7. Backups Aren't Simple(filipovski.net ↗)
    55comments
  8. Small programming tricks(will-keleher.com ↗)
    191comments
  9. Developing provably correct Rust code with Verus(amazon.science ↗)
    4comments
  10. The engineering behind the US Strategic Petroleum Reserve(johnjwang.com ↗)
    52comments
  11. OpenSpec – A lightweight and configurable AI spec framework(openspec.dev ↗)
    37comments
  12. The Return of Sail Power: Cargo Ships Are Turning Back to the Wind(gcaptain.com ↗)
    12comments
  13. A 32-Year-Old Bug Walks into a Telnet Server(watchtowr.com ↗)
    1comments
  14. Performance Improvements in .NET 11(devblogs.microsoft.com/dotnet ↗)
    39comments
  15. Part-human part-mouse brain developed in science breakthrough(bbc.com ↗)
    5comments
  16. Reversing Factorio's RNG(gegell.github.io ↗)
    20comments
  17. HarnessTax: How Much Does the Harness Matter for Coding Agents?(harnesstax.github.io ↗)
    17comments
  18. Japan's book scene is moving from bookstores to libraries(untranslatedjp.substack.com ↗)
    51comments
  19. Show HN: An e-ink frame that hears birds and draws them as 1800s illustrations(github.com/arnegiacomo ↗)
    240comments
  20. AWS says it can't restore some data from mideast facilities struck by Iran(wsj.com ↗)
    232comments
  21. Mapsnap: Automated Georeferencing for Historic Sanborn Insurance Maps(danvk.org ↗)
    1comments
  22. Pangram – AI detector for text and images(pangram.com ↗)
    8comments
  23. Anecdotally, programmers dislike "reduce"(evanhahn.com ↗)
    172comments
  24. Reverse-engineered Jev-like model(github.com/vinnylarouge ↗)
    14comments
  25. Monsanto's Cruel, and Dangerous, Monopolization on American Farming (2008)(vanityfair.com ↗)
    1comments
  26. Australia says it could follow Canada in forging deeper ties with EU(independent.co.uk ↗)
    137comments
  27. Dream-RSI: Recursive Self-Improvement through Evolving Worlds(arxiv.org ↗)
    49comments
  28. Anatomy of a Texture(agentlien.github.io ↗)
    14comments
  29. Why Does the Universe Expand?(cosmicave.org ↗)
    28comments
  30. The DeepMind Institute(deepmind.com ↗)
    50comments

Part-human part-mouse brain developed in science breakthrough

8 pointsby 2h agobbc.com
5 comments
19m agoHN ↗

Great news: we're excellent at curing mice of diseases. All this time we've been trying to find drugs that have the same effect in humans as they do in mice, but until now no one has had the insight or bravery to ask the question, "What if we just made people more mouse?" Exciting stuff.

18m agoHN ↗

The scientists said their work, published in the journal Nature, was carried out with independent ethical scrutiny.

oh, I guess there's nothing to be concerned about.

14m agoHN ↗

Does this remind anyone of that novel Flowers for Algernon..?

6m agoHN ↗

I feel like it's going to be difficult to characterize how mental illness translates to mice, even if you get human cells in there. ("psychiatric disorders" = mental illness)